Muscle Loss & Drugs Like Ozempic – What is the Evidence?

The advent of GLP-1 receptor agonists, such as semaglutide (marketed as Ozempic and Wegovy), has brought promising prospects for weight loss and overall metabolic health improvement (Kim & Kim, 2020). These medications have demonstrated their effectiveness in shedding unwanted pounds and potentially enhancing cardiovascular and metabolic well-being. However, this scientific inquiry delves into a pertinent concern: does the pursuit of weight loss through these pharmacological interventions come at the expense of one’s invaluable muscle mass (Srikanthan & Karlamangla, 2014)? This article will examine the current body of evidence on the impact of GLP-1 receptor agonists on muscle mass and strength, shedding light on whether these benefits indeed come with a price (Ashtary-Larky et al., 2020).

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How “Ozempic” Works – Weight Loss, Weight Regain, & Neuroscience

How do drugs like Ozempic (semaglutide) cause weight loss? What happens when someone comes off of these drugs? In this episode, we discuss how these drugs (GLP-1 receptor agonists) target specific areas in the brain to suppress appetite and facilitate weight loss. We also discuss clinical trials data suggesting that these drugs and/or the weight loss that they facilitate may have cardioprotective effects. Lastly, we will also examine evidence regarding weight regain when coming off of these drugs and common side effects.